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Article

The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians.

PLoS genetics - 1 Feb 2021

Sun Hanxiao, Lin Meng, Russell Emily M, Minster Ryan L, Chan Tsz Fung, Dinh Bryan L, Naseri Take, Reupena Muagututi'a Sefuiva, Lum-Jones Annette, Cheng Iona, Wilkens Lynne R, Le Marchand Loïc, Haiman Christopher A, Chiang Charleston W K

Abstract excerpt

Epidemiological studies of obesity, Type-2 diabetes (T2D), cardiovascular diseases and several common cancers have revealed an increased risk in Native Hawaiians compared to European- or Asian-Americans living in the Hawaiian islands. However, there remains a gap in our understanding of the genetic factors that affect the health of Native Hawaiians. To fill this gap, we studied the genetic risk factors at both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33571193
DOI: 10.1371/journal.pgen.1009273
PMCID: PMC7877570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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