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Genome-wide Association Study of Subcortical Brain Structures in Japanese Ancestry: The Tohoku Medical Megabank Brain Magnetic Resonance Imaging Study

2026-02-12

Abstract excerpt

<title>Abstract</title> <p> Subcortical brain volumes have been extensively mapped by genome-wide association studies (GWASs) in Europeans, but their genetic architecture in East Asians remains unclear. We conducted GWASs on magnetic resonance imaging derived volumes of eight subcortical structures in 9,225 Japanese participants aged 21.6–88.0 years (mean 54.0 ± 15.5 years) from the Tohoku Medical Megabank Brain...

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Literature Corpus work: 4520bac7-81d1-5e42-bc2b-e58405e7a94f
DOI: 10.21203/rs.3.rs-8692327/v1

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