Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetic architecture of human amygdala volumes and their overlap with common brain disorders.

Translational psychiatry - 11 Mar 2023

Ou Ya-Nan, Wu Bang-Sheng, Ge Yi-Jun, Zhang Yi, Jiang Yu-Chao, Kuo Kevin, Yang Liu, Tan Lan, Feng Jian-Feng, Cheng Wei, Yu Jin-Tai

Abstract excerpt

The amygdala is a crucial interconnecting structure in the brain that performs several regulatory functions, yet its genetic architectures and involvement in brain disorders remain largely unknown. We carried out the first multivariate genome-wide association study (GWAS) of amygdala subfield volumes in 27,866 UK Biobank individuals. The whole amygdala was segmented into nine nuclei groups using Bayesian amygdala...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Amygdala

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bayes Theorem

Share to Brain Diseases

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 36906575
DOI: 10.1038/s41398-023-02387-5
PMCID: PMC10008562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetic architecture of human amygdala volumes and their overlap with common brain disorders.PMID 36906575Read ↗

The Genetic Architecture of Amygdala Nuclei.Semantic proximity Read ↗

Genetic Architecture of Subcortical Brain Structures in Over 40,000 Individuals WorldwideSemantic proximity Read ↗

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestriesSemantic proximity Read ↗

Amygdala subdivisions exhibit aberrant whole-brain functional connectivity in relation to stress intolerance and psychotic symptoms in 22q11.2DSSemantic proximity Read ↗

Genomic analysis of intracranial and subcortical brain volumes yields polygenic scores accounting for variation across ancestries.Semantic proximity Read ↗

Genetic correlations between subcortical brain volumes and psychiatric disorders.Semantic proximity Read ↗

Mapping Focal and Generalized Effects of Common Genetic Variants on Human Brain StructureSemantic proximity Read ↗

Genetic Links Between Subcortical Brain Morphometry and Suicide Attempt Risk in Children and Adults.Semantic proximity Read ↗

GWAS of 19,629 individuals identifies novel genetic variants for regional brain volumes and refines their genetic co-architecture with cognitive and mental health traitsSemantic proximity Read ↗

Subcortical brain alterations in carriers of genomic copy number variantsSemantic proximity Read ↗

The Genetic Architecture of the Human Corpus Callosum and its SubregionsSemantic proximity Read ↗

Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.