Article

Extracellular signal-Regulated Kinase 5 (ERK5) is required for the Yes-associated protein (YAP) co-transcriptional activity

2022-07-11

Abstract excerpt

<title>Abstract</title> <p>YES-associated protein (YAP) is a transcriptional cofactor with a key role in the regulation of several cellular processes, including proliferation, differentiation and epithelial-to-mesenchymal transition (EMT), by integrating multiple cell autonomous and microenvironmental cues. YAP overexpression was found in different types of human cancer where it is associated with the acquisition...

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Literature Corpus work: 443dc249-1350-58c0-af2e-65931b27d1a9
DOI: 10.21203/rs.3.rs-1784733/v1

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