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Article

The role of the Hippo pathway in human disease and tumorigenesis

18 Jul 2014

Abstract excerpt

Understanding the molecular nature of human cancer is essential to the development of effective and personalized therapies. Several different molecular signal transduction pathways drive tumorigenesis when deregulated and respond to different types of therapeutic interventions. The Hippo signaling pathway has been demonstrated to play a central role in the regulation of tissue and organ size during development....

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PMID: 25097728
DOI: 10.1186/2001-1326-3-25

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