Article

D3 dopamine receptors implicate a striatal neuronal subtype in the aversive effects of the antipsychotic drug quetiapine

2025-04-20

Abstract excerpt

Second generation antipsychotics (SGAs) are widely used clinical tools; yet, they often cause negative side effects and take weeks to become effective, leading to poor patient compliance. The effect/side effect profile of individual SGAs is highly variable, and the mechanisms that underlie this variability are not well understood. Here, we identify a role of type 3 dopamine receptor (D3R) neurons in the Nucleus Ac...

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Literature Corpus work: 43c8b359-e8a3-5422-a75d-3f4c9f071c04
DOI: 10.1101/2025.04.15.649037

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D3 dopamine receptors implicate a striatal neuronal subtype in the aversive effects of the antipsychotic drug quetiapineDOI 10.1101/2025.04.15.649037Read

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