Article
The cytidine deaminase APOBEC3A is required for large ribosomal subunit biogenesis
2023-02-20
Abstract excerpt
Cancer initiates as a consequence of genomic mutations, and its subsequent progression relies on increased production of ribosomes to maintain high levels of protein synthesis for unchecked cell growth. Recently, cytidine deaminases have been uncovered as sources of mutagenesis in cancer. To form more established connections between these two cancer driving processes, we interrogated the cytidine deaminase family...
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Identifiers and source
- Literature Corpus work
- 43a5951f-4beb-5b24-9c8a-a63126bb20b2
- DOI
- 10.1101/2023.02.20.529126