Article

A method to map and interpret pleiotropic loci using summary statistics of multiple traits

2020-06-17

Abstract excerpt

1 The identification of pleiotropic loci and the interpretation of the associations at these loci are essential to understand the shared etiology of related traits. A common approach to map pleiotropic loci is to use an existing meta-analysis method to combine summary statistics of multiple traits. This strategy does not take into account the complex genetic architectures of traits such as genetic correlations and...

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Literature Corpus work: 436d5eb7-3039-534c-99fd-828e25981787
DOI: 10.1101/2020.06.16.155879

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