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Article

PRIMe: a method for characterization and evaluation of pleiotropic regions from multiple genome-wide association studies.

Bioinformatics (Oxford, England) - 1 May 2011

Huang Jie, Johnson Andrew D, O'Donnell Christopher J

Abstract excerpt

MOTIVATION: The concept of pleiotropy was proposed a century ago, though up to now there have been insufficient efforts to design robust statistics and software aimed at visualizing and evaluating pleiotropy at a regional level. The Pleiotropic Region Identification Method (PRIMe) was developed to evaluate potentially pleiotropic loci based upon data from multiple genome-wide association studies (GWAS). METHODS:...

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PMID: 21398673
DOI: 10.1093/bioinformatics/btr116
PMCID: PMC3109517

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ABO
BRAP
FTO
GCKR

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