Article

CD1d acts as a ligand of PIRA2 to promote macrophage activation in nonalcoholic fatty liver disease

2025-12-04

Abstract excerpt

<title>Abstract</title> <p>Liver inflammation is a key driver of nonalcoholic fatty liver disease (NAFLD) and its progressive subtype, nonalcoholic steatohepatitis (NASH). Macrophages, as central players in the innate immune response, are crucial to disease pathogenesis; however, the upstream events that initiate their activation remain poorly defined. Here, we employed a cell-based chimeric receptor screening sy...

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Literature Corpus work: 43559b4a-a5b9-5b57-95d7-f43432244d25
DOI: 10.21203/rs.3.rs-8110440/v1

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