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Homologous recombination deficiency and Cyclin E1 amplification are correlated with immune cell infiltration and survival in high-grade serous ovarian cancer.

2022-07-05

Abstract excerpt

<title>Abstract</title> <p>How the tumor’s genetic make up (i.e. molecular profiles) is associated with changes in the tumor microenvironment (TME) in high-grade serous ovarian cancer (HGSOC) is incompletely understood, while these factors influence survival. To investigate this we analyzed the TME and molecular profiles (homologous recombination deficiency (HRD) and Cyclin E1 (<italic>CCNE1</italic>) amplificati...

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Literature Corpus work
4346c21a-803f-54fc-a6cf-2f9b84ecce27
DOI
10.21203/rs.3.rs-1776569/v1
Open publication

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