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Post-Transcriptional Modification by Alternative Splicing and Pathogenic Splicing Variants in Cardiovascular Development and Congenital Heart Defects

2022-12-27

Abstract excerpt

Advancements in genomics, bioinformatics and genome editing have uncovered new dimensions in gene regulation. Post-transcriptional modifications by the alternative splicing of mRNA transcripts are critical regulatory mechanisms of mammalian gene expression. In the heart, there is an expanding interest in elucidating the role of alternative splicing in transcriptome regulation. Substantial efforts have been directe...

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Literature Corpus work
42f8f83e-581f-551b-8064-b794634578e7
DOI
10.20944/preprints202209.0479.v2
Open publication

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Post-Transcriptional Modification by Alternative Splicing and Pathogenic Splicing Variants in Cardiovascular Development and Congenital Heart DefectsDOI 10.20944/preprints202209.0479.v2
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