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Article

The alternative heart: impact of alternative splicing in heart disease.

Journal of cardiovascular translational research - 1 Dec 2013

Lara-Pezzi Enrique, Gómez-Salinero Jesús, Gatto Alberto, García-Pavía Pablo

Abstract excerpt

Alternative splicing is the main driver of protein diversity and allows the production of different proteins from each gene in the genome. Changes in exon exclusion, intron retention or the use of alternative splice sites can alter protein structure, localisation, regulation and function. In the heart, alternative splicing of sarcomeric genes, ion channels and cell signalling proteins can lead to...

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Identifiers

PMID: 23775418
DOI: 10.1007/s12265-013-9482-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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