Article

Molecular convergence of risk variants for congenital heart defects leveraging a regulatory map of the human fetal heart

2024-11-21

Abstract excerpt

Congenital heart defects (CHD) arise in part due to inherited genetic variants that alter genes and noncoding regulatory elements in the human genome. These variants are thought to act during fetal development to influence the formation of different heart structures. However, identifying the genes, pathways, and cell types that mediate these effects has been challenging due to the immense diversity of cell types i...

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Literature Corpus work: 8a29e853-b88d-54f2-8da7-5e04aab135cb
DOI: 10.1101/2024.11.20.24317557

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