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Article

Therapeutic potential of alternative splicing in cardiovascular diseases.

EBioMedicine - 1 Mar 2024

Cao Jun, Wei Ziyu, Nie Yu, Chen Hou-Zao

Abstract excerpt

RNA splicing is an important RNA processing step required by multiexon protein-coding mRNAs and some noncoding RNAs. Precise RNA splicing is required for maintaining gene and cell function; however, mis-spliced RNA transcripts can lead to loss- or gain-of-function effects in human diseases. Mis-spliced RNAs induced by gene mutations or the dysregulation of splicing regulators may result in frameshifts,...

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Identifiers

PMID: 38350330
DOI: 10.1016/j.ebiom.2024.104995
PMCID: PMC10874720

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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