Article

Alternative splicing dynamics during human cardiac development <i>in vivo</i> and <i>in vitro</i>

2025-03-24

Abstract excerpt

<h4>ABSTRACT</h4> Cardiomyocytes differentiated in vitro from human induced pluripotent stem cells (iPSC-CMs) are increasingly used in studies of disease mechanisms, drug development, toxicity testing, and regenerative medicine. Alternative splicing (AS), a crucial mechanism for regulating gene expression during development, plays a pivotal role in cardiac differentiation and maturation. However, the extent to w...

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Literature Corpus work: a7ee9671-da58-5beb-a15a-067fe643fc6a
DOI: 10.1101/2025.03.21.642423

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