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Interkingdom glycine conjugates of indole-3-carboxylates are Ah receptor ligands

2026-02-15

Abstract excerpt

Substituted indoles are conserved metabolites across all kingdoms of life and may function as a mediators of inter- and intra-species communication. Indole-3-carboxylates (indole-3-acetic acid (IAA) and indole-3-propionic acid (IPA)) represent abundant tryptophan-derived AHR agonists in human serum, potentially influencing AHR-dependent physiology. LC-MS analysis of mouse serum, urine and cecal/fecal contents reve...

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Literature Corpus work
42f6e773-318f-5180-b0ad-7d7b5863bb12
DOI
10.64898/2026.02.13.705761
Open publication

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