Article

Substrate availability and dietary fibre regulate metabolism of tryptophan by human gut microbes

2023-06-05

Abstract excerpt

Tryptophan is catabolized by gut microbes, resulting in a wide range of metabolites implicated in both beneficial and adverse host effects. However, it remains elusive how the gut microbial tryptophan metabolism is governed either towards indole, associated with adverse effects in chronic kidney disease, or towards indolelactic acid (ILA) and indolepropionic acid (IPA), associated with protective effects in type 2...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8f6889ed-0db3-57cf-949d-572a9f18f635
DOI: 10.1101/2023.06.05.543658

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Substrate availability and dietary fibre regulate metabolism of tryptophan by human gut microbesDOI 10.1101/2023.06.05.543658Read

Microbiota-derived indoles alleviate intestinal inflammation and modulate microbiome by microbial cross-feedingSemantic proximity Read

Tryptophan Metabolites And Their Predicted Microbial Sources In Fecal Samples Of Healthy IndividualsSemantic proximity Read

Tryptophan Metabolites Along the Microbiota-Gut-Brain Axis: An Interkingdom Communication System Influencing the Gut in Health and DiseaseSemantic proximity Read

Microbial modulation of tryptophan metabolism links gut microbiota to disease and its treatmentSemantic proximity Read

Tryptophan metabolism as a target in gut microbiota, ageing and kidney diseaseSemantic proximity Read

Tryptophan metabolism and the gut-brain axis: focus on specific gut microbial generaSemantic proximity Read

Tryptophan as a Central Hub for Host/Microbial SymbiosisSemantic proximity Read

Tryptophan Metabolism by Gut Microbiome and Gut-Brain-Axis: An in silico AnalysisSemantic proximity Read

Indoles as gut microbial pharmaco-metabolites : targets, mechanisms and consequences for obesity and cardiometabolic diseasesSemantic proximity Read

Circulating levels of the anti-oxidant indoleproprionic acid are associated with higher gut microbiome diversitySemantic proximity Read

Indoles: metabolites produced by intestinal bacteria capable of controlling liver disease manifestationSemantic proximity Read

The tryptophan metabolic pathway of the microbiome and host cells in health and diseaseSemantic proximity Read