Article

Altered Default Mode Network Is Associated With Cognitive Impairment in Cadasil as Revealed by Multimodal Neuroimaging

2021-07-06

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) caused by mutations in NOTCH3 gene is a hereditary cerebral small vessel disease, manifesting with stroke, cognitive impairment and mood disturbances. Functional or structural changes in the default mode network (DMN), which plays important roles in cognitive and...

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Literature Corpus work: 42cb8b8e-8a2d-5820-b566-a748faa00513
DOI: 10.21203/rs.3.rs-658208/v1

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