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Article

CADASIL as a Useful Medical Model and Genetic Form of Vascular Depression.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry - 1 Jul 2017

Park Joon Hyuk, Jeon Bong-Hee, Lee Jung Seok, Newhouse Paul A, Taylor Warren D, Boyd Brian D, Kim Ki Woong, Kim Moon-Doo

Abstract excerpt

OBJECTIVE: The main magnetic resonance imaging (MRI) findings of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) are white matter hyperintensities (WMHs), lacunar infarctions, and cerebral microbleeds (CMBs). The purpose of this study was to investigate the effects of these three neuroimaging markers of CADASIL on depression to determine whether CADASIL is a...

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Source

Identifiers

PMID: 28434675
DOI: 10.1016/j.jagp.2017.03.013

Genes

NOTCH3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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