Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish.

BMC biology - 5 Feb 2009

van der Aa Lieke M, Levraud Jean-Pierre, Yahmi Malika, Lauret Emilie, Briolat Valérie, Herbomel Philippe, Benmansour Abdenour, Boudinot Pierre

Abstract excerpt

BACKGROUND: In mammals, the members of the tripartite motif (TRIM) protein family are involved in various cellular processes including innate immunity against viral infection. Viruses exert strong selective pressures on the defense system. Accordingly, antiviral TRIMs have diversified highly through gene expansion, positive selection and alternative splicing. Characterizing immune TRIMs in other vertebrates may...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Motifs
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to COS Cells

Share to Gene Duplication

Share to Multigene Family

Share to Oncorhynchus mykiss

Share to Selection, Genetic

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 19196451
DOI: 10.1186/1741-7007-7-7
PMCID: PMC2657112

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish.PMID 19196451Read ↗

Fish 'n' TRIMs.Semantic proximity Read ↗

Origin and Evolution of TRIM Proteins: New Insights from the Complete TRIM Repertoire of Zebrafish and PufferfishSemantic proximity Read ↗

Identification of Fish Interferon Stimulated Genes and Their Antiviral MechanismsSemantic proximity Read ↗

Positive Selection and Duplication of Bat TRIM Family ProteinsSemantic proximity Read ↗

Zebrafish TRIM2a promotes virus replication via ubiquitination of IRF3 and autophagic cargo receptor p62Semantic proximity Read ↗

Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary propertiesSemantic proximity Read ↗

Grouper TRIM23 exerts antiviral activity against iridovirus and nodavirusSemantic proximity Read ↗

Fish TRIM16L exerts negative regulation on antiviral immune response against grouper iridovirusesSemantic proximity Read ↗

Interferon-stimulated genes in zebrafish and human define an ancient arsenal of antiviral immunitySemantic proximity Read ↗

Genome-Wide Characterization of Zebrafish Endogenous Retroviruses Reveals Unexpected Diversity in Genetic Organizations and Functional Potentials.Semantic proximity Read ↗

Structure and evolutionary history of a large family of NLR proteins in the zebrafishSemantic proximity Read ↗

The confounding complexity of innate immune receptors within and between teleost species.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.