Article
A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish.
BMC biology - 5 Feb 2009
van der Aa Lieke M, Levraud Jean-Pierre, Yahmi Malika, Lauret Emilie, Briolat Valérie, Herbomel Philippe, Benmansour Abdenour, Boudinot Pierre
Abstract excerpt
BACKGROUND: In mammals, the members of the tripartite motif (TRIM) protein family are involved in various cellular processes including innate immunity against viral infection. Viruses exert strong selective pressures on the defense system. Accordingly, antiviral TRIMs have diversified highly thro...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
