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Article

Antiviral effects of interferon-stimulated genes in bats

18 Aug 2023

Abstract excerpt

The interferon pathway is the first line of defense in viral infection in all mammals, and its induction stimulates broad expression of interferon-stimulated genes (ISGs). In mice and also humans, the antiviral function of ISGs has been extensively studied. As an important viral reservoir in nature, bats can coexist with a variety of pathogenic viruses without overt signs of disease, yet only limited data are...

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PMID: 37661999
DOI: 10.3389/fcimb.2023.1224532

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