Article

Analyses of allele age and fitness impact reveal human beneficial alleles to be older than neutral controls

2023-10-10

Abstract excerpt

A classic population genetic prediction is that alleles experiencing directional selection should swiftly traverse allele frequency space, leaving detectable reductions in genetic variation in linked regions. However, despite this expectation, identifying clear footprints of beneficial allele passage has proven to be surprisingly challenging. We addressed the basic premise underlying this expectation by estimating...

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Literature Corpus work: 426c731e-c6d0-5c3e-aa96-86d5b82c0cdf
DOI: 10.1101/2023.10.09.561569

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