Article
Estimating Time to the Common Ancestor for a Beneficial Allele.
Molecular biology and evolution - 1 Apr 2018
Smith Joel, Coop Graham, Stephens Matthew, Novembre John
Abstract excerpt
The haplotypes of a beneficial allele carry information about its history that can shed light on its age and the putative cause for its increase in frequency. Specifically, the signature of an allele's age is contained in the pattern of variation that mutation and recombination impose on its haplotypic background. We provide a method to exploit this pattern and infer the time to the common ancestor of a...
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