Article

Human demographic history has amplified the effects of background selection across the genome

2017-08-29

Abstract excerpt

Natural populations often grow, shrink, and migrate over time. Demographic processes such as these can impact genome-wide levels of genetic diversity. In addition, genetic variation in functional regions of the genome can be altered by natural selection, which drives adaptive mutations to higher frequencies or purges deleterious ones. Such selective processes impact not only the sites directly under selection but...

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Literature Corpus work: c93c51e6-f2b9-5d73-987e-9b1126e0363e
DOI: 10.1101/181859

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