Article
Detecting recent positive selection in the human genome from haplotype structure.
Nature - 24 Oct 2002
Sabeti Pardis C, Reich David E, Higgins John M, Levine Haninah Z P, Richter Daniel J, Schaffner Stephen F, Gabriel Stacey B, Platko Jill V, Patterson Nick J, McDonald Gavin J, Ackerman Hans C, Campbell Sarah J, Altshuler David, Cooper Richard, Kwiatkowski Dominic, Ward Ryk, Lander Eric S
Abstract excerpt
The ability to detect recent natural selection in the human population would have profound implications for the study of human history and for medicine. Here, we introduce a framework for detecting the genetic imprint of recent positive selection by analysing long-range haplotypes in human popula...
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