Article
Large-scale omics data reveal the cooperation of mutation-circRNA-miRNA-target gene network in liver cancer oncogenesis.
Future oncology (London, England) - 1 Jan 2022
Li Jian, Yu Chun-Peng, Li Qun, Chang Shuai, Xie Ling-Ling, Wang Song
Abstract excerpt
Aims: Clarifying the initial trigger of the differentially expressed genes in cancers helps researchers understand the cellular system as a whole network. Materials & methods: We retrieve the transcriptome and translatome of tumor and normal tissues from ten liver cancer patients and define differentially expressed genes and tumor-specific mutations. We associate the oncogenesis with the mutations by target...
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