Article

Correlated Drug Action as a Baseline Model for Combination Therapy in Patient Cohorts and Cell Cultures

2021-05-25

Abstract excerpt

Identifying and characterizing the effect of combination therapies is of paramount importance in various diseases, including cancer. Various competing null models have been proposed to serve as baselines against which to compare the effect of drug combinations. In this work, we introduce Correlated Drug Action (CDA), a baseline model for the study of drug combinations in both cell cultures and in patient populatio...

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Identifiers and source

Literature Corpus work: 4204c3b2-fe9c-5ee5-a56c-6283bcf616dc
DOI: 10.1101/2021.05.23.445343

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