Article
Distinguishing rational from irrational applications of pharmacogenetic synergies from the bench to clinical trials.
Cell cycle (Georgetown, Tex.) - 1 Jun 2007
Hucl Tomas, Gallmeier Eike, Kern Scott E
Abstract excerpt
Single therapeutic agents very often fail in unselected patients. It is therefore commonplace to combine an agent specifically with a selected patient subgroup or with another agent. To support such efforts, it is useful to clarify the distinctions between the terms and the mathematical models us...
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