Article

Non-parametric synergy modeling with Gaussian processes

2021-04-02

Abstract excerpt

<h4>Background</h4> Understanding the synergetic and antagonistic effects of combinations of drugs and toxins is vital for many applications, including treatment of multifactorial diseases and ecotoxicological monitoring. Synergy is usually assessed by comparing the response of drug combinations to a predicted non-interactive response from reference (null) models. Possible choices of null models are Loewe additiv...

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Literature Corpus work: e738ad0d-f393-5f93-8658-3ec3b9e0b5b1
DOI: 10.1101/2021.04.02.438180

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