Article
A statistical framework for defining synergistic anticancer drug interactions
2025-09-30
Abstract excerpt
Synergistic drug combinations have the potential to delay drug resistance and improve clinical outcomes in patients with advanced cancers. However, current cell-based screens lack robust statistical assessment to identify significant synergistic interactions for downstream experimental or clinical validation. Leveraging a large-scale dataset that systematically evaluated more than 2,000 drug combinations across 12...
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Identifiers and source
- Literature Corpus work
- 13f18e8c-cc6a-5220-9c0a-c05bb19a00f6
- DOI
- 10.1101/2025.09.29.679166