Article

Genome-wide association study of appendicular lean mass in UK Biobank cohort

2019-05-21

Abstract excerpt

Lean body mass (LBM), an important physiological measure, has a strong genetic determination. To clarify its genetic basis, a large-scale genome-wide association study (GWAS) of appendicular lean mass (ALM) was conducted in 450,580 UK Biobank subjects. A total of 717 variants (p<5×10 −9 ) from 561 loci were identified, which were replicated across genders (achieving p<5×10 −5 in both genders). The identified var...

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Literature Corpus work: 41f4e471-5dc7-5341-b13f-23bd2725e276
DOI: 10.1101/643536

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