Article
Bivariate genome-wide association analyses of femoral neck bone geometry and appendicular lean mass.
PloS one - 1 Jan 2011
Sun Lu, Tan Li-Jun, Lei Shu-Feng, Chen Xiang-Ding, Li Xi, Pan Rong, Yin Fang, Liu Quan-Wei, Yan Xiao-Feng, Papasian Christopher J, Deng Hong-Wen
Abstract excerpt
OBJECTIVE: Femoral neck geometric parameters (FNGPs), such as periosteal diameter (W), cross-sectional area (CSA), cortical thickness (CT), buckling ratio (BR), and section modulus (Z), are highly genetically correlated with body lean mass. However, the specific SNPs/genes shared by these phenotypes are largely unknown. METHODS: To identify the specific SNPs/genes shared between FNGPs and appendicular lean mass...
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