Article
A causal relationship between appendicular lean mass and atrial fibrillation: A two sample Mendelian randomization study.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jun 2024
Song Yongfei, Zheng Zequn, Hu Jiale, Lian Jiangfang
Abstract excerpt
BACKGROUND AND AIM: The relationship between appendicular lean mass (ALM) and most cardiovascular events has been established, but the direct association between ALM and atrial fibrillation (AF) remains uncertain. METHODS AND RESULTS: Herein, we identified 494 single-nucleotide polymorphisms (SNPs) strongly associated with ALM as instrumental variables (P < 5E-8) based on a genome-wide association study (GWAS)...
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