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High-Dimensional Protein Analysis Uncovers Distinct Immunological and Stromal Signatures Between Primary and Metastatic Pancreatic Ductal Adenocarcinoma

2025-04-18

Abstract excerpt

<h4>ABSTRACT</h4> Our understanding of the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME) primarily stems from murine models or primary patient tumors. While metastatic tumors have generally less immune infiltration compared to primary tumors, the specific cellular features of metastatic PDAC remain understudied. This knowledge gap is impactful as most patients present with metastatic diseas...

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Literature Corpus work
41ba26f9-fef2-5a45-9be1-4c23a0d752aa
DOI
10.1101/2025.04.18.649381
Open publication

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High-Dimensional Protein Analysis Uncovers Distinct Immunological and Stromal Signatures Between Primary and Metastatic Pancreatic Ductal AdenocarcinomaDOI 10.1101/2025.04.18.649381
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