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Article

Integrated Genomic and Immunophenotypic Classification of Pancreatic Cancer Reveals Three Distinct Subtypes with Prognostic/Predictive Significance.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2018

Wartenberg Martin, Cibin Silvia, Zlobec Inti, Vassella Erik, Eppenberger-Castori Serenella, Terracciano Luigi, Eichmann Micha David, Worni Mathias, Gloor Beat, Perren Aurel, Karamitopoulou Eva

Abstract excerpt

Purpose: Current clinical classification of pancreatic ductal adenocarcinoma (PDAC) is unable to predict prognosis or response to chemo- or immunotherapy and does not take into account the host reaction to PDAC cells. Our aim is to classify PDAC according to host- and tumor-related factors into clinically/biologically relevant subtypes by integrating molecular and microenvironmental findings.Experimental Design:...

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Identifiers

PMID: 29661773
DOI: 10.1158/1078-0432.CCR-17-3401

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FOXP3
ATM
JAK3
SMAD4
STK11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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