Article

Multi-omics analysis of the molecular response to glucocorticoids - insights into shared genetic risk from psychiatric to medical disorders

2023-12-05

Abstract excerpt

<h4>Background</h4> Glucocorticoids play a crucial role as mediators of negative health effects associated with chronic stress, including increased risk for psychiatric disorders as well as cardiovascular and metabolic diseases. This study investigates the impact of genetic variants and glucocorticoid receptor (GR)-activation on gene expression and DNA methylation in peripheral blood and the relationship of these...

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Literature Corpus work: 417a8e92-011b-5fb2-8660-3c93dbfbac7c
DOI: 10.1101/2023.12.05.23299430

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