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Article

Dynamic regulation of glucocorticoid signalling in health and disease

3 Sept 2011

Abstract excerpt

Activation of the glucocorticoid receptor (GR) by endogenous and synthetic glucocorticoids regulates hundreds of genes to control regulatory networks in development, metabolism, cognition and inflammation. Elucidation of the mechanisms that regulate glucocorticoid action has highlighted the dynamic nature of hormone signalling and provides novel insights into genomic glucocorticoid actions. The major factors that...

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Share to Adrenal Hormones and Disorders
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PMID: 21891790
DOI: 10.1093/rheumatology/ker215

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