Article

Impact of HLA divergence on humoral response to SARS-CoV-2 and HBV vaccines in the liver transplantation setting

2022-08-30

Abstract excerpt

<h4>Background</h4> Organ transplant recipients are at high risk of viral infections but show lower humoral vaccine responsiveness than immunocompetent individuals. HLA evolutionary divergence (HED) quantifies the sequence differences between homologous HLA alleles and reflects the breadth of the immunopeptidome presented to T lymphocytes. <h4>Methods</h4> We retrospectively investigated the impact of HED on humor...

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Literature Corpus work: 415464c9-40ac-5003-b799-e168dfefe58f
DOI: 10.1101/2022.08.29.22279247

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