Article

Influence of HLA class II polymorphism on predicted cellular immunity against SARS-CoV-2 at the population and individual level

2020-12-26

Abstract excerpt

Development of effective adaptive immune responses after coronavirus disease 2019 (COVID-19) and after vaccination against SARS-CoV-2 is predicated on recognition of viral peptides, presented in the context of HLA class II molecules, by CD4 + T-cells. We capitalised on extensive high resolution HLA data deposited in the National Marrow Donor Program registry to obtain detailed information on human HLA haplotype f...

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Literature Corpus work: fc76f79c-03d5-52f0-a2c2-b4e23452670f
DOI: 10.1101/2020.12.24.424326

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