Article

The NK receptor NKp46 recognizes ecto-calreticulin on ER-stressed cells

2021-11-03

Abstract excerpt

Natural killer cells (NK) are a first line of immune defense to eliminate infected, transformed and stressed cells by releasing cytotoxic granules 1 . NK activation is controlled by the balance of signals transmitted by activating and inhibitory receptors but activating receptor engagement is required to trigger cytotoxicity. The activating receptor NKp46, encoded by the NCR1 gene, is expressed by virtually all...

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Literature Corpus work: 412cd2cf-0778-5fbb-8f81-e77da35c3b3c
DOI: 10.1101/2021.10.31.466654

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