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Article

Phenome-wide investigation of the causal associations between childhood BMI and adult trait outcomes: a two-sample Mendelian randomization study

26 Mar 2021

Abstract excerpt

BACKGROUND: Childhood obesity is reported to be associated with the risk of many diseases in adulthood. However, observational studies cannot fully account for confounding factors. We aimed to systematically assess the causal associations between childhood body mass index (BMI) and various adult traits/diseases using two-sample Mendelian randomization (MR). METHODS: After data filtering, 263 adult traits...

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PMID: 33771188
DOI: 10.1186/s13073-021-00865-3

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