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Evaluating the direct effects of childhood adiposity on adult systemic-metabolism: A multivariable Mendelian randomization analysis

2020-08-31

Abstract excerpt

<h4>Background</h4> Individuals who are obese in childhood have an elevated risk of cardiometabolic disease in adulthood. However, whether childhood adiposity directly impacts intermediate markers of this risk, independent of adult adiposity, is unclear. <h4>Methods and Results</h4> We conducted a multivariable Mendelian randomization (MR) study to simultaneously evaluate the effects of childhood and adulthood bod...

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Literature Corpus work
b64d3d7f-d21a-512c-9be6-604b94a6af41
DOI
10.1101/2020.08.25.20181412
Open publication

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