Article

Single-cell RNA-seq of mouse dopaminergic neurons informs candidate gene selection for sporadic Parkinson’s disease

2017-06-09

Abstract excerpt

<h4>ABSTRACT</h4> Genetic variation modulating risk of sporadic Parkinson’s disease (PD) has been primarily explored through genome wide association studies (GWAS). However, like many other common genetic diseases, the impacted genes remain largely unknown. Here, we used single-cell RNA-seq to characterize dopaminergic (DA) neuron populations in the mouse brain at embryonic and early postnatal timepoints. These d...

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Literature Corpus work: 40cbaafc-5917-5f6f-9d18-52b926a6e465
DOI: 10.1101/148049

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