Article

Evaluating the mouse neural precursor line, SN4741, as a suitable proxy for midbrain dopaminergic neurons

2023-02-16

Abstract excerpt

To overcome the ethical and technical limitations of in vivo human disease models, the broader scientific community frequently employs model organism-derived cell lines to investigate of disease mechanisms, pathways, and therapeutic strategies. Despite the widespread use of certain in vitro models, many still lack contemporary genomic analysis supporting their use as a proxy for the affected human cells and tissue...

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Literature Corpus work: 52dab7ff-92bf-5205-968e-0fa0418dc5a3
DOI: 10.21203/rs.3.rs-2520557/v1

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