Article

A map of direct TF-DNA interactions in the human genome

2018-08-17

Abstract excerpt

<h4>ABSTRACT</h4> Chromatin immunoprecipitation followed by sequencing (ChIP-seq) is the most popular assay to identify genomic regions, called ChIP-seq peaks, that are bound in vivo by transcription factors (TFs). These regions are derived from direct TF-DNA interactions, indirect binding of the TF to the DNA (through a co-binding partner), nonspecific binding to the DNA, and noise/bias/artifacts. Delineating th...

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Literature Corpus work: 606d4a7c-f648-5202-bb72-2d77a5c09ab6
DOI: 10.1101/394205

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