Back to search

Article

Beyond the Genome: Microproteins Unveiling New Dimensions in Cancer

2024-06-03

Abstract excerpt

In the complex landscape of cancer biology, the discovery of microproteins has triggered a paradigm shift, thereby, challenging the conventional conceptions of gene regulation. Though overlooked for years, these entities encoded by the small open reading frames (100-150 codons), have a significant impact on various cellular processes. As the pioneers of precision medicine delve deeper into genome and proteome, the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a1b7838c-c2ed-54be-a720-33d4244c27fe
DOI
10.22541/au.171742829.91739763/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Beyond the Genome: Microproteins Unveiling New Dimensions in CancerDOI 10.22541/au.171742829.91739763/v1
The microproteome of cancer: From invisibility to relevanceSemantic proximity
Exploring the Dark Matter of Human Proteome: Emerging Role of Non-canonical Open Reading Frame (ncORF) in Cancer Diagnosis, Biology, and TherapySemantic proximity
MicroProteins: Expanding functions and novel modes of regulation.Semantic proximity
Exploring the Dark Matter of Human Proteome: The Emerging Role of Non-Canonical Open Reading Frame (ncORF) in Cancer Diagnosis, Biology, and TherapySemantic proximity
Cross-Species Genome-Wide Identification of Evolutionary Conserved MicroProteins.Semantic proximity
Some like it translated: small ORFs in the 5′UTRSemantic proximity
The diverse functions of viral microproteinsSemantic proximity
Nascent alt-protein chemoproteomics reveals a repressor of ribosome biogenesisSemantic proximity
Discovery of evolutionarily extended <i>cis</i> -regulatory overlapping genes expanding the protein universe from animals to humansSemantic proximity
Most non-canonical proteins uniquely populate the proteome or immunopeptidomeSemantic proximity
Molecular mechanisms of non-genetic aberrant peptide production in cancer.Semantic proximity
How mutations of intrinsically disordered protein regions can drive cancerSemantic proximity
Select a neighboring publication to make it the new centre.