Article

African-specific genetic loci determine iron status and risk of severe malaria and bacteremia in African children

2025-06-25

Abstract excerpt

<title>Abstract</title> <p>Iron is essential for both humans and pathogens, yet its genetic regulation remains understudied in African populations. We conducted genome-wide association studies for six iron-related biomarkers in 3928 children from five sites across Africa, with replication in 2868 African American adults and investigated associations with severe malaria and bacteremia. We identified previously unr...

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Literature Corpus work: 2c721878-4b0a-5833-9b9b-61fb02bca29e
DOI: 10.21203/rs.3.rs-6853969/v1

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