Article

Mapping the lineage relationship between CXCR5 <sup>+</sup> and CXCR5 <sup>-</sup> CD4 <sup>+</sup> T cells in HIV infected human lymph nodes

2019-01-31

Abstract excerpt

<h4>Summary</h4> CXCR5 is a key surface marker expressed on follicular helper T (T FH ) cells. We report here B cell help functionality in a population of CD4 + T cells isolated from primary human lymph nodes (LN) that lacked CXCR5 expression. This CXCR5 - subset is distinguished from other CXCR5 - CD4 + T cells by high PD-1 expression. Accumulation of CXCR5 - PD-1 + T cells correlated with peripheral CD4...

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Literature Corpus work: 401cda9a-74b5-5d02-8611-2f4bb3bc69ec
DOI: 10.1101/537050

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