Article

<i>CXCR5</i> gene expression in human lymph node CD8 <sup>+</sup> T cells is regulated by DNA methylation and nucleosomal occupancy

2020-07-17

Abstract excerpt

CD8 + T cells play an important role in viral and tumour control. However, in human lymph nodes (LNs), only a small subset of CD8 + T cells called follicular CD8 + T cells (fCD8s) expresses CXCR5, the chemokine receptor required for cell migration into B cell follicles, thought to promote immune evasion. Here we obtained LNs from HIV infected persons to investigate regulation of CXCR5 expression in lymphoid CD8...

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Literature Corpus work: 52ee5538-8baf-57cf-ac45-06798a3c4280
DOI: 10.1101/2020.07.17.208470

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